Cholecystokinin Facilitates Neuronal Excitability in the Entorhinal Cortex via Activation
نویسندگان
چکیده
Cholecystokinin Facilitates Neuronal Excitability in the Entorhinal Cortex via Activation 1 of TRPC-like Channels 2 Shouping Wang, An-Ping Zhang, Lalitha Kurada, Toshimitsu Matsui and Saobo Lei 3 From Department of Pharmacology, Physiology and Therapeutics, School of Medicine and 4 Health Sciences, University of North Dakota, Grand Forks, ND58203, USA; Department of 5 Anesthesiology, Sun Yat-sen Memorial hospital, Sun Yat-sen University, 107 West Yanjiang 6 Road, Guangzhou, Guangdong Province, P.R. China. Zip code: 510120; Hematology, 7 Department of Medicine, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, 8 Chuo-ku, Kobe 650-1700, Japan. 9 § These authors contribute equally to this work. 10 11
منابع مشابه
Cholecystokinin facilitates neuronal excitability in the entorhinal cortex via activation of TRPC-like channels.
Cholecystokinin (CCK) is one of the most abundant neuropeptides in the brain, where it interacts with two G protein-coupled receptors (CCK-1 and CCK-2). Activation of both CCK receptors increases the activity of PLC, resulting in increases in intracellular calcium ion (Ca(2+)) release and activation of PKC. Whereas high density of CCK receptors has been detected in the superficial layers of the...
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